ESR1 and GPX1 genes expression level in human malignant and non-malignant breast tissues | Zendy

Magdalena Beata Król | Zendy; Michał Galicki | Zendy; Peter Grešner | Zendy; Edyta Wieczorek | Zendy; Ewa Jabłońska | Zendy; Edyta Reszka | Zendy; Zbigniew Morawiec | Zendy; Wojciech Wąsowicz | Zendy; Jolanta Gromadzińska | Zendy

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ESR1 and GPX1 genes expression level in human malignant and non-malignant breast tissues

Author(s) -

Magdalena Beata Król,

Michał Galicki,

Peter Grešner,

Edyta Wieczorek,

Ewa Jabłońska,

Edyta Reszka,

Zbigniew Morawiec,

Wojciech Wąsowicz,

Jolanta Gromadzińska

Publication year - 2018

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2016_1425

Subject(s) - gpx1 , breast cancer , estrogen receptor alpha , estrogen receptor , cancer research , gene expression , cancer , biology , medicine , gene , endocrinology , glutathione peroxidase , genetics , oxidative stress , catalase

The aim of this study was to establish whether the gene expression of estrogen receptor alpha (encoded by ESR1) correlates with the expression of glutathione peroxidase 1 (encoded by GPX1) in the tumor and adjacent tumor-free breast tissue, and whether this correlation is affected by breast cancer. Such relationships may give further insights into breast cancer pathology with respect to the status of estrogen receptor.

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