Mechanisms of type I interferon action and its role in infections and diseases transmission in mammals | Zendy

Weronika Ratajczak | Zendy; PauliiedźwiedzkaRystwej | Zendy; Beata TokarzDeptuła | Zendy; Wiesław Deptuła | Zendy

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Mechanisms of type I interferon action and its role in infections and diseases transmission in mammals

Author(s) -

Weronika Ratajczak,

PauliiedźwiedzkaRystwej,

Beata TokarzDeptuła,

Wiesław Deptuła

Publication year - 2017

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2016_1403

Subject(s) - interferon , biology , interferon type i , transmission (telecommunications) , immunology , gene , action (physics) , microbiology and biotechnology , virology , genetics , physics , engineering , quantum mechanics , electrical engineering

Interferons (IFNs) are pivotal regulators of immunological processes. This paper describes mainly type I interferons -α and -β and their recently recounted signaling pathways, especially connected with ISGs - interferon stimulated genes, having a crucial role in regulating IFN recruitment. Moreover, the paper shows the data on the role of interferons -α and -β in infections - not only commonly known viral infections, but also bacterial, fungal and parasitic.

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