Evaluation of clinical usefulness of serum neopterin determination in children with bacterial infections | Zendy

Katarzyna PlataNazar | Zendy; Grażyna Łuczak | Zendy; Anna Liberek | Zendy; Julita Dudzińska-Gehrmann | Zendy; Katarzyna Sznurkowska | Zendy; Piotr Landowski | Zendy; Barbara Kamińska | Zendy

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Evaluation of clinical usefulness of serum neopterin determination in children with bacterial infections

Author(s) -

Katarzyna PlataNazar,

Grażyna Łuczak,

Anna Liberek,

Julita Dudzińska-Gehrmann,

Katarzyna Sznurkowska,

Piotr Landowski,

Barbara Kamińska

Publication year - 2015

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2014_893

Subject(s) - neopterin , urinary system , medicine , urine , gastroenterology , etiology , immunology , hepatology , procalcitonin , clinical microbiology , sepsis , microbiology and biotechnology , biology

Neopterin (NPT) (6-D-erythro-trihydroxypropyl pteridin) is one of the indicators of the immune system activity. Elevated neopterin concentration occurs in diseases mostly involving stimulation of cellular immunity. The determination of neopterin concentration, usually in blood serum and urine but also in many other bodily fluids, has already been applied in many areas of medicine, such as transfusiology, transplantology, oncology, infectious diseases and autoimmunological diseases.

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