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A universal flu vaccine.
Author(s) -
Małgorzata Kęsik-Brodacka,
Grażyna Płucienniczak
Publication year - 2014
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.2014_1874
Subject(s) - virology , pandemic , vaccination , immunity , immunology , influenza vaccine , medicine , immune system , biology , covid-19 , disease , infectious disease (medical specialty) , pathology
Influenza is a global health concern. The single most effective way of protecting people against influenza infection and disease is vaccination. However, currently available vaccines against influenza induce only strain-specific immunity, and do not elicit long-lasting serum antibody titers. Therefore, they are ineffective in the case of possible pandemics. There is an urgent need for a new generation vaccine which would induce broad and long-lasting immune protection against antigenically distinct flu viruses. The paper presents recent achievements and the challenges in the field of universal vaccine construction.

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