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Biased versus unbiased randomness in homo-polymers and copolymers of amino acids in the prebiotic world.
Author(s) -
F. G. Mosqueira,
Alicia Negron,
Sergio E. Ramos,
Carlos Polanco
Publication year - 2012
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.2012_2089
Subject(s) - amino acid , randomness , polymerization , polymer , prebiotic , abiogenesis , chemistry , chemical evolution , polarity (international relations) , copolymer , biology , biochemistry , organic chemistry , genetics , physics , mathematics , statistics , stars , astronomy , cell
The polymerization of amino acids under anhydrous prebiotic conditions was first studied several decades ago. Here we use a stochastic model stressing the relevant role of the polarity of amino acids in the formation of oligopeptides in a prebiotic milieu. Our goal is to outline the predominance of co-polypeptides over homo-polypeptides, resulting not only from the randomness, but also from polarity properties of amino acids. Our results conclude that there was a higher probability of the formation of co-polypeptides than of homo-polymers. Besides, we may hypothesize that the former would have a more ample spectrum of possible chemical functions than homo-polypeptides.

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