Chemical synthesis of dolichyl phosphates, their analogues and derivatives and application of these compounds in biochemical assays. | Zendy

Leonid L. Danilov | Zendy; Т. Н. Дружинина | Zendy

Open Access

Chemical synthesis of dolichyl phosphates, their analogues and derivatives and application of these compounds in biochemical assays.

Author(s) -

Leonid L. Danilov,

Т. Н. Дружинина

Publication year - 2007

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2007_3135

Subject(s) - isoprene , chemistry , chemical synthesis , chemical modification , combinatorial chemistry , biochemistry , organic chemistry , in vitro , copolymer , polymer

Several methods for simple and efficient chemical synthesis of dolichyl phosphates and their analogues and derivatives are briefly summarized with a special emphasis on chemical modification of phosphoryl group and preparation of dolichyl phosphates labelled at the omega-end and at the gamma-isoprene unit of the isoprene chain by fluorescent groups, 2-aminopyridine and 1-aminonaphtalene residues. Additionally, data on biochemical assays with application of the compounds mentioned above are presented.

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