A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line. | Zendy

Shuwen Guan | Zendy; Leng-Xin Duan | Zendy; Yuanyuan Li | Zendy; Ben-Xiang Wang | Zendy; Qiuli Zhou | Zendy

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A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line.

Author(s) -

Shuwen Guan,

Leng-Xin Duan,

Yuanyuan Li,

Ben-Xiang Wang,

Qiuli Zhou

Publication year - 2006

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2006_3354

Subject(s) - cervus , antler , cell culture , microbiology and biotechnology , cell , cell growth , amino acid , chemistry , velvet , biology , biochemistry , genetics , zoology , ecology , organic chemistry

A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg x L(-1) and 5-80 mg x L(-1), respectively).

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