Effect of anthocyanins on selected biochemical parameters in rats exposed to cadmium. | Zendy

Edward Kowalczyk | Zendy; Anna Kopff | Zendy; Paweł Fijałkowski | Zendy; Maria Kopff | Zendy; J Niedworok | Zendy; Jan Błaszczyk | Zendy; Józef Kędziora | Zendy; Piotr Tyślerowicz | Zendy

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Effect of anthocyanins on selected biochemical parameters in rats exposed to cadmium.

Author(s) -

Edward Kowalczyk,

Anna Kopff,

Paweł Fijałkowski,

Maria Kopff,

J Niedworok,

Jan Błaszczyk,

Józef Kędziora,

Piotr Tyślerowicz

Publication year - 2003

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2003_3707

Subject(s) - cadmium , chemistry , cadmium poisoning , cadmium chloride , alanine aminotransferase , cadmium exposure , bilirubin , urea , physiology , biochemistry , pharmacology , food science , medicine , biology , organic chemistry

Cadmium is a dangerous occupational and environmental toxin. It accumulates in the human organism mainly in liver and kidneys. Cadmium half-life is about 10 years, so the symptoms of cadmium intoxication may occur several years after the exposure. Until now in treating intoxication with this metal chelating compounds have been used, burdened with numerous undesirable symptoms. In our investigations anthocyanins from Aronia melanocarpa were used to reduce the harmful results caused by cadmium. Administering anthocyanins with cadmium chloride resulted in a statistically significant decrease of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity, concentration of bilirubin and urea in blood serum and decreased cadmium cumulation in liver and kidneys in relation to animals receiving cadmium chloride only.

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