Lymphocyte labile iron pool, plasma iron, transferrin saturation and ferritin levels in colon cancer patients.
Author(s) -
Daniel Gackowski,
Marcin Kruszewsk,
Zbigniew Banaszkiewicz,
Arkadiusz Jawień,
Ryszard Ólinski
Publication year - 2002
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.2002_3845
Subject(s) - transferrin saturation , ferritin , transferrin , serum iron , saturation (graph theory) , chemistry , colorectal cancer , medicine , metabolism , iron status , carcinoma , endocrinology , gastroenterology , biochemistry , iron deficiency , cancer , biology , serum ferritin , anemia , hemoglobin , mathematics , combinatorics
Patients with colorectal carcinoma showed statistically significant lower values of transferrin saturation, total iron binding capacity and serum iron level as compared with control group, while the level of ferritin and the size of labile iron pool in carcinoma patients were higher, although this difference was not statistically significant. Our observations are in favour of the hypothesis which suggests that changes in iron metabolism restrict iron availability for tumour cells and as consequence, slow their growth.
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