Structure and functions of 5S rRNA. | Zendy

M. Barciszewska | Zendy; M. Szymański | Zendy; Volker A. Erdmann | Zendy; J Barciszewski | Zendy

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Structure and functions of 5S rRNA.

Author(s) -

M. Barciszewska,

M. Szymański,

Volker A. Erdmann,

J Barciszewski

Publication year - 2001

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2001_5126

Subject(s) - ribosome , ribozyme , transfer rna , 23s ribosomal rna , ribosomal rna , ribonucleoprotein , eukaryotic ribosome , protein subunit , rna , eukaryotic large ribosomal subunit , protein biosynthesis , biochemistry , ribonucleoprotein particle , messenger rna , translation (biology) , 5s ribosomal rna , ribosomal protein , chemistry , gene

The ribosome is a macromolecular assembly that is responsible for protein biosynthesis in all organisms. It is composed of two-subunit, ribonucleoprotein particles that translate the genetic material into an encoded polypeptides. The small subunit is the site of codon-anticodon interaction between the messenger RNA (mRNA) and transfer RNA (tRNA) substrates, and the large subunit catalyses peptide bond formation. The peptidyltransferase activity is fulfilled by 23S rRNA, which means that ribosome is a ribozyme. 5S rRNA is a conserved component of the large ribosomal subunit that is thought to enhance protein synthesis by stabilizing ribosome structure. This paper shortly summarises new results obtained on the structure and function of 5S rRNA.

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