Fluorescence decay time distribution analysis of cyclic enkephalin analogues; influence of solvent and Leu configuration in position 5 on conformation. | Zendy

Joanna Malicka | Zendy; Robert Ganzynkowicz | Zendy; M Groth | Zendy; Cezary Czaplewski | Zendy; Jerzy Karolczak | Zendy; Adam Liwo | Zendy; Wiesław Wiczk | Zendy

Open Access

Fluorescence decay time distribution analysis of cyclic enkephalin analogues; influence of solvent and Leu configuration in position 5 on conformation.

Author(s) -

Joanna Malicka,

Robert Ganzynkowicz,

M Groth,

Cezary Czaplewski,

Jerzy Karolczak,

Adam Liwo,

Wiesław Wiczk

Publication year - 2001

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2001_5115

Subject(s) - chemistry , fluorescence , acceptor , distribution (mathematics) , solvent , peptide , stereochemistry , crystallography , photochemistry , biophysics , organic chemistry , biochemistry , biology , mathematical analysis , physics , mathematics , quantum mechanics , condensed matter physics

Lifetime distribution analysis were performed to study the influence of Leu configuration in position 5 on changes of the peptide chain of cyclic analogues of enkephalins containing a fluorescence donor and acceptor in different solvents. The configuration change of Leu5 in all the analogues of enkephalins studied which contain donor-acceptor pairs has no apparent influence on Trp lifetime distributions. In contrast, there is a significant solvent effect on the shape of lifetime distribution.

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