Evolutionary principles for generating protein mimetics: directed assembly of peptide loops on topological templates.
Author(s) -
D Banfi,
Bhubaneswar Mandal,
M Mutter,
Luc Patiny
Publication year - 2001
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.2001_3872
Subject(s) - template , protein evolution , peptide , computational biology , topology (electrical circuits) , chemistry , biology , microbiology and biotechnology , biophysics , nanotechnology , biochemistry , materials science , gene , engineering , electrical engineering
A novel methodology for the reversible competitive condensation of peptide loops to chemoreactive topological templates is presented.
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