Effect of stress on the life span of the yeast Saccharomyces cerevisiae. | Zendy

Agata Święciło | Zendy; Z Krawiec | Zendy; J Wawryn | Zendy; Grzegorz Bartosz | Zendy; Tomasz Biliński | Zendy

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Effect of stress on the life span of the yeast Saccharomyces cerevisiae.

Author(s) -

Agata Święciło,

Z Krawiec,

J Wawryn,

Grzegorz Bartosz,

Tomasz Biliński

Publication year - 2000

Publication title -

acta biochimica polonica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.452

H-Index - 78

eISSN - 1734-154X

pISSN - 0001-527X

DOI - 10.18388/abp.2000_4015

Subject(s) - saccharomyces cerevisiae , yeast , life span , osmotic shock , superoxide dismutase , stress (linguistics) , biology , span (engineering) , longevity , shock (circulatory) , antioxidant , biochemistry , genetics , medicine , gene , linguistics , philosophy , civil engineering , evolutionary biology , engineering

A correlation is known to exist in yeast and other organisms between the cellular resistance to stress and the life span. The aim of this study was to examine whether stress treatment does affect the generative life span of yeast cells. Both heat shock (38 degrees C, 30 min) and osmotic stress (0.3 M NaCl, 1 h) applied cyclically were found to increase the mean and maximum life span of Saccharomyces cerevisiae. Both effects were more pronounced in superoxide dismutase-deficient yeast strains (up to 50% prolongation of mean life span and up to 30% prolongation of maximum life span) than in their wild-type counterparts. These data point to the importance of the antioxidant barrier in the stress-induced prolongation of yeast life span.

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