p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland.
Author(s) -
Aleksandra Dybikowska,
A Dettlaff,
Krzysztof Konopa,
Anna J. Podhajska
Publication year - 2000
Publication title -
acta biochimica polonica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.452
H-Index - 78
eISSN - 1734-154X
pISSN - 0001-527X
DOI - 10.18388/abp.2000_3970
Subject(s) - cervical cancer , gene polymorphism , polymorphism (computer science) , medicine , genotype , arginine , genetics , cancer research , gene , oncology , gastroenterology , biology , cancer , amino acid
A polymorphism at codon 72 of gene p53 results in the presence of either arginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of healthy women from Poland. Our results do not confirm the hypothesis that the p53 codon polymorphism could play a role as a factor for squamous carcinoma of the cervix.
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