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Glycolic acid peels have been shown in many studies to improve the appearance of photoaged skin. Vitamin C is known to be a potent natural antioxidant and plays an important role in the collagen biosynthetic pathway. In this study, we report our clinical experience with 70% glycolic acid peel added with vitamin C. We found that all parameters of photoaging, in particular the composite wrinkling score, discolouration score and the global photoaged score, showed statistically significant improvement. Patient satisfaction also revealed improvement in keeping with the physician assessment. It is also associated with an excellent safety profile. In conclusion, a combination of 70% glycolic acid with vitamin C chemical peel is a well-tolerated effective treatment of photoaging in Asian skin.

The efficacy and safety of a 70% glycolic acid peel with vitamin C for the treatment of photoaging