Correction of glabellar protrusion after botulinum toxin injection for forehead wrinkles

Botulinum toxin blocks the release of the neurotransmitter acetylcholine and helps to treat wrinkles. The efficacy and safety of botulinum toxin injection for upper facial wrinkles were established in several previous studies. Common side effects include transient headache, bruising, eyebrow ptosis and eyelid swelling. No adverse life threatening events or long-term complications have been reported. However, there have been a few reports on site-specific side effects, except for eyebrow ptosis or eyelid swelling. Two previous cases showing exaggerated glabellar wrinkles after botulinum toxin injection for forehead horizontal lines reported that no specific treatment for the exaggeration of wrinkles were done and it was left to slowly recede. In the present report, we highlighted a patient, whose significant glabellar protrusion was rapidly and effectively corrected with the use of botulinum toxin injection.