An unusual presentation of brain metastasis: Multiple skull and parenchymal lesions masquerading as infective etiology

Brain metastasis is a common occurrence in many solid malignancies. The radiological diagnosis is often determined with magnetic resonance imaging (MRI). We report a case of a 60-year-old lady who had headaches for two months, followed by seizures. Her MRI showed multiple skull and brain parenchymal lesions simulating an infective etiology. Further investigations revealed a primary carcinoma of the right lung. The patient showed improvement in symptoms once chemotherapy was started. Brain metastases can masquerade as infective lesions and delay the diagnosis of malignancy. A high index of suspicion is required to allow a prompt diagnosis and treatment.