Open AccessEffect of nintedanib thermo-sensitive hydrogel on neovascularization in alkali burn rat model
Author(s) -
Yan Gong,
Guohai Wu,
Lingyi Zhang,
Zhe Zhang,
Yanhong Liao,
Xiaotian Liu
Publication year - 2020
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2020.06.04
Subject(s) - corneal neovascularization , neovascularization , medicine , ophthalmology , dexamethasone , cd31 , cornea , vascular endothelial growth factor , h&e stain , saline , pathology , staining , angiogenesis , vegf receptors
NTH becomes colloidal at body temperature, which is beneficial for releasing the drug slowly and can significantly inhibit the neovascularization of corneal induced by alkali burn in rats.
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