SUMOylation and deacetylation affect NF-κB p65 activity induced by high glucose in human lens epithelial cells
Author(s) -
Xiao Han,
Xiaoxuan Dong,
Mingyu Shi,
Feng Li,
Xinling Wang,
Jinsong Zhang,
Qi-Chang Yan
Publication year - 2019
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2019.09.01
Subject(s) - mg132 , sumo protein , western blot , nf κb , microbiology and biotechnology , acetylation , iκbα , electrophoretic mobility shift assay , immunofluorescence , blot , ubiquitin , gene expression , chemistry , proteasome inhibitor , apoptosis , biology , biochemistry , gene , antibody , immunology
To explore the effects of IκBα SUMOylation and NF-κB p65 deacetylation on NF-κB p65 activity induced by high glucose in cultured human lens epithelial cells (HLECs).
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