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Activation of the TRAAK two-pore domain potassium channels in rd1 mice protects photoreceptor cells from apoptosis
Author(s) -
Lei Wang,
Kangpei Shi,
Han Li,
Hao Huang,
WenBin Wu,
Chu-Sheng Cai,
Xiaotong Zhang,
Xiaobo Zhu
Publication year - 2019
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2019.08.03
Subject(s) - outer nuclear layer , apoptosis , riluzole , microbiology and biotechnology , intraperitoneal injection , h&e stain , immunostaining , downregulation and upregulation , retina , medicine , pathology , staining , biology , pharmacology , immunohistochemistry , glutamate receptor , biochemistry , receptor , neuroscience , gene
To investigate the expression of TWIK-related arachidonic acid-stimulated K + channel (TRAAK) in retinal degeneration mice (rd1) and further evaluate how TRAAK affect photoreceptor cell apoptosis.

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