Expression of multidrug-resistance associated proteins in human retinoblastoma treated by primary enucleation | Zendy

Li-Juan Tang | Zendy; LiJun Zhou | Zendy; Wenxin Zhang | Zendy; Jianyan Lin | Zendy; Yongping Li | Zendy; Huasheng Yang | Zendy; Ping Zhang | Zendy

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Expression of multidrug-resistance associated proteins in human retinoblastoma treated by primary enucleation

Author(s) -

Li-Juan Tang,

LiJun Zhou,

Wenxin Zhang,

Jianyan Lin,

Yongping Li,

Huasheng Yang,

Ping Zhang

Publication year - 2018

Publication title -

international journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 29

eISSN - 2227-4898

pISSN - 2222-3959

DOI - 10.18240/ijo.2018.09.06

Subject(s) - medicine , retinoblastoma , multiple drug resistance , enucleation , cancer research , ophthalmology , bioinformatics , drug resistance , genetics , surgery , gene , biology

To reveal the expression of multidrug-resistance associated proteins: glutathione-S-transferase π (GSTπ), P-glycoprotein (P-gp) and vault protein lung resistance protein (LRP) in retinoblastoma (RB) without any conservative treatment before primary enucleation and to correlate this expression with histopathological tumor features.

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