Mesenchymal stem cells-derived exosomes ameliorate blue light stimulation in retinal pigment epithelium cells and retinal laser injury by VEGF-dependent mechanism | Zendy

Guanghui He | Zendy; Wei Zhang | Zendy; Yingxue Ma | Zendy; Jing Yang | Zendy; Li Chen | Zendy; Jian Song | Zendy; Song Chen | Zendy

Open Access

Mesenchymal stem cells-derived exosomes ameliorate blue light stimulation in retinal pigment epithelium cells and retinal laser injury by VEGF-dependent mechanism

Author(s) -

Guanghui He,

Wei Zhang,

Yingxue Ma,

Jing Yang,

Li Chen,

Jian Song,

Song Chen

Publication year - 2018

Publication title -

international journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 29

eISSN - 2227-4898

pISSN - 2222-3959

DOI - 10.18240/ijo.2018.04.04

Subject(s) - medicine , mesenchymal stem cell , retinal , retinal pigment epithelium , microbiology and biotechnology , microvesicles , mechanism (biology) , vegf receptors , stimulation , stem cell , ophthalmology , cancer research , pathology , biology , microrna , biochemistry , gene , philosophy , epistemology

To observe the effect of exosomes derived from human umbilical cord blood mesenchymal stem cells (hUCMSCs) on the expression of vascular endothelial growth factor-A (VEGF-A) in blue light injured human retinal pigment epithelial (RPE) cells and laser-induced choroidal neovascularization (CNV) in rats.

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