Aralia elata inhibits neurodegeneration by downregulating O-GlcNAcylation of NF-κB in diabetic mice | Zendy

Seong-Jae Kim | Zendy; Minjun Kim | Zendy; Mee-Young Choi | Zendy; Yoonsook Kim | Zendy; Ji-Myong Yoo | Zendy; Eun-Kyung Hong | Zendy; Sunmi Ju | Zendy; Wan-Sung Choi | Zendy

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Aralia elata inhibits neurodegeneration by downregulating O-GlcNAcylation of NF-κB in diabetic mice

Author(s) -

Seong-Jae Kim,

Minjun Kim,

Mee-Young Choi,

Yoonsook Kim,

Ji-Myong Yoo,

Eun-Kyung Hong,

Sunmi Ju,

Wan-Sung Choi

Publication year - 2017

Publication title -

international journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 29

eISSN - 2227-4898

pISSN - 2222-3959

DOI - 10.18240/ijo.2017.08.03

Subject(s) - neurodegeneration , streptozotocin , ctl* , terminal deoxynucleotidyl transferase , endocrinology , medicine , apoptosis , downregulation and upregulation , diabetes mellitus , tunel assay , biology , immunology , biochemistry , immune system , immunohistochemistry , disease , gene , cd8

To investigate the role of O-GlcNAcylation of nuclear factor-kappa B (NF-κB) in retinal ganglion cell (RGC) death and analysedthe effect of Aralia elata (AE) on neurodegeneration in diabetic mice.

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