Induction of vascular endothelial growth factor receptor expression in human umbilical vein endothelial cells after repeated bevacizumab treatment in vitro | Zendy

Ji Eun Lee | Zendy; Jin Young Kim | Zendy; Jae Ho Jung | Zendy; DongHoon Shin | Zendy; Sung Who Park | Zendy

Open Access

Induction of vascular endothelial growth factor receptor expression in human umbilical vein endothelial cells after repeated bevacizumab treatment in vitro

Author(s) -

Ji Eun Lee,

Jin Young Kim,

Jae Ho Jung,

DongHoon Shin,

Sung Who Park

Publication year - 2017

Publication title -

international journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 29

eISSN - 2227-4898

pISSN - 2222-3959

DOI - 10.18240/ijo.2017.07.07

Subject(s) - bevacizumab , umbilical vein , medicine , vascular endothelial growth factor , angiogenesis , pharmacology , in vitro , human umbilical vein endothelial cell , cytotoxicity , vascular endothelial growth factor a , western blot , neovascularization , andrology , vegf receptors , chemotherapy , biology , biochemistry , gene

To investigate the mechanism underlying the loss of responsiveness to anti-vascular endothelial growth factor (VEGF) treatment after repeated injections for choroidal neovascularization, VEGF and VEGF receptor (VEGFR) expressions were evaluated following repeated bevacizumab treatments in hypoxic human umbilical vein endothelial cells (HUVECs) in vitro .

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research