Open AccessPigment epithelium-derived factor protects retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction
Author(s) -
Shuwei Tian,
Yuan Ren,
Jin-Zhi Pei,
Bai-Chao Ren,
Yuan He
Publication year - 2017
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2017.07.05
Subject(s) - pedf , apoptosis , annexin , microbiology and biotechnology , viability assay , fetal bovine serum , biology , medicine , retinal , biochemistry , cell
To investigate the potential of pigment epithelium-derived factor (PEDF) to protect the immortalized rat retinal ganglion cells-5 (RGC-5) exposed to CoCl 2 -induced chemical hypoxia.
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