Open AccessExpression and role of specificity protein 1 in the sclera remodeling of experimental myopia in guinea pigs
Author(s) -
Bo Jiang,
WU Zhang-you,
Zi-Cheng Zhu,
Genjie Ke,
Yuechun Wen,
Siqin Sun
Publication year - 2017
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2017.04.08
Subject(s) - sclera , medicine , transforming growth factor , downregulation and upregulation , ophthalmology , microbiology and biotechnology , andrology , chemistry , biology , biochemistry , gene
To study the expression of collagen I and transcription factor specificity protein 1 (Sp1), a transforming growth factor-β1 (TGF-β1) downstream target, and reveal the impact of the TGF-β1-Sp1 signaling pathway on collagen remodeling in myopic sclera.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom