Differential expression of breast cancer-resistance protein, lung resistance protein, and multidrug resistance protein 1 in retinas of streptozotocin-induced diabetic mice | Zendy

Mengshuang Li | Zendy; Meng Xin | Zendy; Chuanlong Guo | Zendy; Guiming Lin | Zendy; Jun Li | Zendy; Xianggen Wu | Zendy

Open Access

Differential expression of breast cancer-resistance protein, lung resistance protein, and multidrug resistance protein 1 in retinas of streptozotocin-induced diabetic mice

Author(s) -

Mengshuang Li,

Meng Xin,

Chuanlong Guo,

Guiming Lin,

Jun Li,

Xianggen Wu

Publication year - 2017

Publication title -

international journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 29

eISSN - 2227-4898

pISSN - 2222-3959

DOI - 10.18240/ijo.2017.04.03

Subject(s) - abcg2 , efflux , blood–retinal barrier , medicine , retina , diabetic retinopathy , vascular endothelial growth factor a , vascular endothelial growth factor , pharmacology , cancer research , microbiology and biotechnology , atp binding cassette transporter , endocrinology , diabetes mellitus , biology , transporter , biochemistry , neuroscience , vegf receptors , gene

To investigate the altering expression profiles of efflux transporters such as breast cancer-resistance protein (BCRP), lung resistance protein (LRP), and multidrug resistance protein 1 (MDR1) at the inner blood-retinal barrier (BRB) during the development of early diabetic retinopathy (DR) and/or aging in mice.

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