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Inhibition of choroidal neovascularization by lentivirus-mediated PEDF gene transfer in rats
Author(s) -
Yajie Yu,
Bin Mo,
Lu Liu,
Yankun Yue,
Changli Yue,
Wu Liu
Publication year - 2016
Publication title -
international journal of ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.634
H-Index - 29
eISSN - 2227-4898
pISSN - 2222-3959
DOI - 10.18240/ijo.2016.08.05
Subject(s) - pedf , choroidal neovascularization , green fluorescent protein , lentivirus , medicine , vascular endothelial growth factor , microbiology and biotechnology , ophthalmology , chemistry , biology , retinal , cancer research , immunology , vegf receptors , biochemistry , gene , viral disease , virus
To evaluate the effects of lentivirus-mediated pigment epithelium-derived factor (PEDF) gene transfer performed in treatment of rats with established choroidal neovascularization (CNV), and investigates the mechanism by which PEDF inhibits CNV in rats.

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