Safety and efficacy of photodynamic therapy using BCECF-AM compared to mitomycin C in controlling post-operative fibrosis in a rabbit model of subscleral trabeculectomy | Zendy

Azza Mohamed Ahmed Said | Zendy; Rania Gamal Eldin Zaki | Zendy; Thanaa Helmy Mohamed | Zendy; Manal Salman | Zendy

Open Access

Safety and efficacy of photodynamic therapy using BCECF-AM compared to mitomycin C in controlling post-operative fibrosis in a rabbit model of subscleral trabeculectomy

Author(s) -

Azza Mohamed Ahmed Said,

Rania Gamal Eldin Zaki,

Thanaa Helmy Mohamed,

Manal Salman

Publication year - 2016

Publication title -

international journal of ophthalmology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.634

H-Index - 29

eISSN - 2227-4898

pISSN - 2222-3959

DOI - 10.18240/ijo.2016.03.04

Subject(s) - medicine , trabeculectomy , mitomycin c , intraocular pressure , ophthalmology , glaucoma , fibrosis , wound healing , reduction (mathematics) , photoablation , surgery , anesthesia , laser , geometry , mathematics , excimer laser , physics , optics

To evaluate the safety and efficacy of cellular photoablation using BCECF-AM [2', 7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein, acetoxymethyl ester mixed isomers] as a method to control postoperative fibrosis in subscleral trabeculectomy (SST) compared to mitomycin C (MMC) in a rabbit model.

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