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The review summarizes literature data on the development of drugs based on natural and synthetic  high-polymeric double-stranded RNA, and their antiviral, immunoadjuvant and antitumor properties. Special attention  is paid to cell receptors responding to exogenous dsRNA, the paths of dsRNA-dependent antiviral reaction, ability  of dsRNA to inhibit growth and induce apoptosis ofmalignant cells. It has been shown that enhancing the innate immune  response with dsRNA can be an effective component in improving methods for treating and preventing infectious and  cancer diseases. The further use of dsRNA for the correction of pathological processes of different origin is discussed

Development of drugs on the basis of high-polymeric double-stranded RNA for antiviral and antitumor therapy