English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The purpose of the study was to investigate the features of expression and adiponectin content in the adipocyte  culture of subcutaneous, epicardial, and perivascular adipose tissue and the effect of various doses of rosuvastatin  on these processes. 29 patients with coronary artery disease were examined. Adipocytes were isolated from  the samples of SAT, EAT and PVAT which were taken during coronary artery bypass surgery, followed by cultivation  in the presence of rosuvastatin and evaluation of gene expression and adiponectin concentration. Adipocytes  SAT, EAT and PVAT differed in the level of adiponectin secretion and expression of its gene. On day 1 of cultivation  the expression of the adiponectin gene in the EAT was 2.3 times lower than in the PVAT. On day 2 of cultivation  the expression of the adiponectin gene was reduced both in the EAT and the PVAT as compared to the SAT.  When rosuvastatin was added at a concentration of 1 mmol/L, adiponectin gene expression in PVAT was higher  than when rosuvastatin was added at a concentration of 5 mmol/L, in the adipocyte culture of SAT effect was opposite.  Thus, the adipocytes of EZhT and, to a greater extent, PAS, can be a therapeutic target for statins in the case  of the pathological activation of adipose tissue.

Expression of gene and content of adiponectin in fatty tissue in patients with ischemic heart disease