Pharmacological targets for dislipidemies correction. Opportunities and prospects of therapeutic usage | Zendy

V.A. Kudinov | Zendy; T. S. Zakharova | Zendy; T. I. Torkhovskaya | Zendy; O. M. Ipatova | Zendy; А. I. Archakov | Zendy

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Pharmacological targets for dislipidemies correction. Opportunities and prospects of therapeutic usage

Author(s) -

V.A. Kudinov,

T. S. Zakharova,

T. I. Torkhovskaya,

O. M. Ipatova,

А. I. Archakov

Publication year - 2018

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20186401066

Subject(s) - computer science , risk analysis (engineering) , drug , action (physics) , medicine , computational biology , pharmacology , intensive care medicine , biology , physics , quantum mechanics

Literature data on influence of existing and new groups of drug preparations for dyslipidemias correction are systemized, and molecular mechanisms of their effects are reviewed. The results of experimental and clinical investigations aimed at revealing of new pharmacological targets of dyslipidemias correction were analyzed. The approaches for activation of high density lipoproteins functionality are described. The implementation of alternative preparations with new alternative mechanisms of action may be suggested to improve the effectiveness of traditional treatment in the future.

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