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Endometrial mesenchymal stromal cells (eMSCs), along with mesenchymal stromal cells (MSCs) isolated  from other tissues, are promising for use in regenerative medicine. The benefits of eMSCs include their presence  in adults, simplicity of isolation, high proliferative and differentiation capacity. In this study, we have employed  the flow cytometry technique to assess expression of 28 molecular markers on the surface of two eMSCs cultures.  The culture of MSCs isolated from Wharton's jelly of the umbilical cord (uMSCs) was used as a reference, because  uMSCs were studied in details earlier and demonstrated their effectiveness in vivo. Both types of MSCs demonstrated  similar expression profiles. They included stem cells surface molecules, cell adhesion molecules and their ligands, some  receptor molecules responsible for cell metabolism and proliferation, as well as immunological response molecules.

biomedicinskaâ himiâ

Comparison of the expression profile of surface molecular markers on mesenchymal stromal cell cultures isolated from human endometrium and umbilical cord