The role of vascular endothelial growth factor in the regulation of development and functioning of the brain: new target molecules for pharmacotherapy | Zendy

Valeriia Roslavtceva | Zendy; А. Б. Салмина | Zendy; С. В. Прокопенко | Zendy; Е. А. Пожиленкова | Zendy; И. В. Кобаненко | Zendy; G. G. Rezvitskaya | Zendy

Open Access

The role of vascular endothelial growth factor in the regulation of development and functioning of the brain: new target molecules for pharmacotherapy

Author(s) -

Valeriia Roslavtceva,

А. Б. Салмина,

С. В. Прокопенко,

Е. А. Пожиленкова,

И. В. Кобаненко,

G. G. Rezvitskaya

Publication year - 2016

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20166202124

Subject(s) - neuroprotection , angiogenesis , neurogenesis , vascular endothelial growth factor , neuroscience , arteriogenesis , medicine , pharmacotherapy , brain edema , vegf receptors , pharmacology , psychology , cancer research

Vascular endothelial growth factors (VEGFs) have been shown to participate in atherosclerosis, arteriogenesis, cerebral edema, neuroprotection, neurogenesis, angiogenesis, postischemic brain and vessel repair. Most of these actions involve VEGF-A and the VEGFR-2 receptor. VEGF signaling pathways represent an important potential for treatment of neurological diseases affecting the brain

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