Biological activity and mechanisms of therapeutic action of rosmarinic acid, luteolin and its sulphated derivatives | Zendy

А. М. Попов | Zendy; O. N. Krivoshapko | Zendy; А. А. Климович | Zendy; A. A. Artyukov | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Biological activity and mechanisms of therapeutic action of rosmarinic acid, luteolin and its sulphated derivatives

Author(s) -

А. М. Попов,

O. N. Krivoshapko,

А. А. Климович,

A. A. Artyukov

Publication year - 2016

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20166201022

Subject(s) - rosmarinic acid , luteolin , hyperlipidemia , sulfation , chemistry , biological activity , pharmacology , biochemistry , medicine , diabetes mellitus , flavonoid , antioxidant , in vitro , endocrinology

The review considers recent experimental studies of biological activity and mechanisms of therapeutic action of rosmarinic acid, luteolin and its sulfated derivatives in diseases associated with disorders of carbohydrate and lipid metabolism. Particular attention is focused on the results of studies showing a high therapeutic potential of these phenolic compounds in their prophylactic and therapeutic use at experimental modeling of type 2 diabetes and hyperlipidemia. Based on the analysis of our results and the literature data putative mechanisms of therapeutic action of rosmarinic acid, luteolin and its sulfated derivatives have been proposed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research