Glycine receptors in nervous tissue and their functional role | Zendy

В. Н. Никандров | Zendy; Т. В. Балашевич | Zendy

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Glycine receptors in nervous tissue and their functional role

Author(s) -

В. Н. Никандров,

Т. В. Балашевич

Publication year - 2014

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20146004403

Subject(s) - ionotropic effect , glycine , glycine receptor , receptor , nmda receptor , glutamate receptor , biochemistry , biology , nervous tissue , ionotropic glutamate receptor , microbiology and biotechnology , neuroscience , chemistry , amino acid

The literature data on glycine metabolism in neural tissue, mitochondrial Gly-cleaving system, Gly-catching system in neural and glial cells are summarized. The peculiarities of localization and distribution of specific glycine receptors and binding-sites in nervous tissue of mammals are described. Four types of glycine-binding receptors are described: own specific glycine receptor (Gly-R), ionotropic receptor, which binds N-methyl-D-aspartate selectively (NMDA-R), and ionotropic receptors of g-aminobutyrate (GABA A -R, GABA С -R). The feutures of glycine effects in neuroglial cultures are discussed

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