Metabolic profiling of human blood | Zendy

Oxana P. Trifonova | Zendy; Petr G. Lokhov | Zendy; A. I. Archakov | Zendy

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Metabolic profiling of human blood

Author(s) -

Oxana P. Trifonova,

Petr G. Lokhov,

A. I. Archakov

Publication year - 2014

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20146003281

Subject(s) - metabolomics , computational biology , profiling (computer programming) , metabolite profiling , transcriptome , metabolite , metabolome , organism , proteome , human blood , biology , omics , bioinformatics , computer science , physiology , genetics , gene , biochemistry , gene expression , operating system

Metabolomics is a novel "omics" branch of science intended for studying a comprehensive set of low molecular weight substances (metabolites) of various biological objects. Metabolite profiles represent a molecular phenotype of biological systems and reflect information encoded at the genome level and realized at the transcriptome and proteome levels. Analysis of human blood metabolic profile is universal and promising tool for clinical applications because it is a sensitive measure of both endogenous and exogenous (environmental) factors affected on the patient's organism. Technical implementation of metabolic profiling of blood and statistic analysis of metabolite profiles for effective diagnostics and risk assessments of diseases are discussed in this review.

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