The proinsulin level in the blood of children with type 1 diabetes mellitus of various duration
Author(s) -
N. Yu. Lotosh,
А. А. Селищева,
S.A. Nadorov,
Б. А. Бадыштов,
I.E. Volkov,
S. V. Saveljev
Publication year - 2013
Publication title -
biomeditsinskaya khimiya
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.192
H-Index - 15
eISSN - 2310-6972
pISSN - 2310-6905
DOI - 10.18097/pbmc20135905563
Subject(s) - proinsulin , prohormone , medicine , endocrinology , diabetes mellitus , type 2 diabetes mellitus , pathogenesis , hormone
Proinsulin content was measured in the serum of 82 children (aged from 3 to 14 years) with type 1 diabetes mellitus of various duration. Three groups of patients characterized by low (54%), normal (42%) and high (4%) levels of this prohormone were recognized. No dependence the proinsulin level on the disease term was found. The serum proinsulin level may be used as a parameter specifying the pathogenesis of type 1 diabetes mellitus.
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