Conotoxins: from the biodiversity of gastropods to new drugs | Zendy

Alexander Fedosov | Zendy; Sergei A. Moshkovskii | Zendy; Ksenia G. Kuznetsova | Zendy; Baldomero M. Olivera | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Conotoxins: from the biodiversity of gastropods to new drugs

Author(s) -

Alexander Fedosov,

Sergei A. Moshkovskii,

Ksenia G. Kuznetsova,

Baldomero M. Olivera

Publication year - 2013

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20135903267

Subject(s) - conotoxin , conus , biodiversity , biology , ecology , venom

A review describes general trends in research of conotoxins that are peptide toxins isolated from sea gastropods of the Conus genus, since the toxins were discovered in 1970 . There are disclosed a conotoxin classification, their structure diversity and different ways of action to their molecular targets, mainly, ion channels. In the applied aspect of conotoxin research, drug discovery and development is discussed, the drugs being based on conotoxin structure. A first exemplary drug is a ziconotide, which is an analgesic of new generation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research