Protocols of proteins interactomics: molecular fishing on optical chips and magnetic nanoparticles
Author(s) -
Ivanov As,
П. В. Ершов,
Yuri V. Mezentsev,
Ekaterina V. Poverennaya,
Andrey Lisitsa,
Alexander I. Archakov
Publication year - 2013
Publication title -
biomeditsinskaya khimiya
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.192
H-Index - 15
eISSN - 2310-6972
pISSN - 2310-6905
DOI - 10.18097/pbmc20135902171
Subject(s) - function (biology) , nanoparticle , protein function , computer science , chemistry , nanotechnology , materials science , biology , biochemistry , microbiology and biotechnology , gene
Now it is absolutely clear, that the majority of proteins in living systems function due to interaction with each other in stable or dynamic proteins complexes. Therefore necessity of deeper studies of proteins functions causes expansion of protein-protein interaction research. In the present review the brief description and comparative estimation of experimental methods and protocols of protein interactomics, based on technology of molecular fishing on an optical chips and paramagnetic nanoparticles is given.
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