Particularities of corrective action of polar lipids and bioantioxidants from sea hydrobionts at imbalances of lipid and carbohydrate metabolism | Zendy

O. N. Krivoshapko | Zendy; А. М. Попов | Zendy; A. A. Artyukov | Zendy; E. Ya. Kostetsky | Zendy

Open Access

Particularities of corrective action of polar lipids and bioantioxidants from sea hydrobionts at imbalances of lipid and carbohydrate metabolism

Author(s) -

O. N. Krivoshapko,

А. М. Попов,

A. A. Artyukov,

E. Ya. Kostetsky

Publication year - 2012

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20125802189

Subject(s) - polyunsaturated fatty acid , chemistry , zostera marina , sea urchin , polyphenol , glycolipid , biochemistry , carbohydrate , botany , lipid metabolism , zostera , fatty acid , food science , biology , ecology , antioxidant , ecosystem , seagrass

A total mixture of phospho- and glycolipids from sea macrophytes Sargassum pallidum, Ulva fenestrata, Zostera marina was separated and the fatty acid composition was determined. Biological activity of the mixtures of polar lipids and natural antioxidants echinochrome A from flat sea urchin Scaphechinus mirabilis and polyphenolic complex from sea grass Zostera marina was studied in rats with experimental model of atherosclerosis and diabetes. These experiments revealed optimal compositions for mixtures of polar lipids and antioxidants, which possess high medical-corrective activity. Proposed mechanisms of action of the polar lipids (containing different polyunsaturated fatty acids) and antioxidants studied are presented. These compositions may be used for creation of new biologically-active additives and drugs.

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