The diagnostic value of RNA oncomarkers in evaluation of malignant breast tumors | Zendy

A.G. Globa | Zendy; Ya. I. Alekseev | Zendy; D.A. Varlamov | Zendy; A. A. Vishnevsky | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The diagnostic value of RNA oncomarkers in evaluation of malignant breast tumors

Author(s) -

A.G. Globa,

Ya. I. Alekseev,

D.A. Varlamov,

A. A. Vishnevsky

Publication year - 2011

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20115706677

Subject(s) - mammaglobin , fibroadenoma , medicine , cytokeratin , rna , telomerase , differential diagnosis , pathology , telomerase reverse transcriptase , breast fibroadenoma , breast carcinoma , oncology , breast cancer , biology , cancer , immunohistochemistry , gene , biochemistry

The levels of the RNA oncomarkers, telomerase (hTERT), cytokeratin-19 (CK-19) and mammaglobin (MAM) have been investigated in capillary blood of female patients with mammary ductal carcinoma. The study revealed overexpression of all three factors in patients with this pathology. This overexpression was not found in healthy donors and female patients with mammary fibroadenoma. Levels of the RNA oncomarkers return to the normal level within 10 days after successful tumor resection. These results have been used for the development of diagnostic kits, which may be applicable for differential diagnostics, screening and postoperation monitoring of patients with malignant breast tumors

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research