Nuclear glutathione and its functions | Zendy

V. I. Kulinsky | Zendy; Л. С. Колесниченко | Zendy

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Nuclear glutathione and its functions

Author(s) -

V. I. Kulinsky,

Л. С. Колесниченко

Publication year - 2010

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20105606657

Subject(s) - glutathione , microbiology and biotechnology , nucleus , chemistry , mitochondrion , nuclear localization sequence , biochemistry , glutathione metabolism , enzyme , biophysics , biology

During recent years the nuclear localization of glutathione has been confirmed and this fraction has been quantitatively determined. The nuclear GSH and the enzymes of its metabolism realize independent and important functions. They considerably differ from functions of hyaloplasmic and mitochondrial GSH. Glutathione interacts with regulatory pathways, involved into signal transmission into the nucleus.

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