Study of activity of enzymes of antioxidant system of blood at HIV infection | Zendy

V. V. Kostyushov | Zendy; I. I. Bokal | Zendy; S. A. Petrov | Zendy

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Study of activity of enzymes of antioxidant system of blood at HIV infection

Author(s) -

V. V. Kostyushov,

I. I. Bokal,

S. A. Petrov

Publication year - 2010

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20105605596

Subject(s) - antioxidant , superoxide dismutase , catalase , lipid peroxidation , glutathione reductase , glutathione peroxidase , enzyme , glutathione , biochemistry , gpx4 , chemistry , immunology , biology

HIV infection is accompanied by activation of lipid peroxidation, oxidative modification of lipoprotein complexes, and a decrease in activity of antioxidant enzymes (superoxide dismutase (SOD), catalase and glutathione peroxidase (GP)) in blood serum. A significant increase of glutathione reductase observed under these conditions is considered as a function of the antioxidant defence. These changes were already seen at early (symptomless) stages of this disease, however, at manifested forms they were more pronounced.

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