Glycerolipids of alkyl type - modulators of tumoral cells destruction | Zendy

С. Г. Романова | Zendy; В. Г. Романов | Zendy; Г. А. Серебренникова | Zendy; Alexander А. Shtil | Zendy

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Glycerolipids of alkyl type - modulators of tumoral cells destruction

Author(s) -

С. Г. Романова,

В. Г. Романов,

Г. А. Серебренникова,

Alexander А. Shtil

Publication year - 2010

Publication title -

biomeditsinskaya khimiya

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.192

H-Index - 15

eISSN - 2310-6972

pISSN - 2310-6905

DOI - 10.18097/pbmc20105604457

Subject(s) - alkyl , mechanism of action , mechanism (biology) , chemistry , cytotoxic t cell , action (physics) , combinatorial chemistry , stereochemistry , biochemistry , organic chemistry , philosophy , in vitro , epistemology , physics , quantum mechanics

The review is summarizes current information on biological activity and search of the antineoplastic mechanism of action of alkyl glycerolipids. Special attention is paid to following problems: selective ability phosphorus alkyl glycerolipids, antineoplastic activity, cytostatic and cytotoxic effects of edelfosine and its analogues. The review contains set of the data known for today from the literature, on the possible mechanism cytoyoxic actions of such connections.

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