The Technique of Thyroid Cartilage Scaffold Support Formation for Extrusion-Based Bioprinting
Author(s) -
Nadezhda V. Arguchinskaya,
Е. Е. Бекетов,
Anastas A. Kisel,
Елена Исаева,
E. O. Osidak,
S.P. Domogatsky,
N. V. Mikhailovsky,
F. Е. Sevryukov,
N. K. Silantyeva,
T. A. Agababyan,
С. А. Иванов,
Peter Shegay,
А. Д. Каприн
Publication year - 2024
Publication title -
international journal of bioprinting
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.014
H-Index - 24
eISSN - 2424-7723
pISSN - 2424-8002
DOI - 10.18063/ijb.v7i2.348
Subject(s) - scaffold , biofabrication , biomedical engineering , materials science , cartilage , computer science , tissue engineering , anatomy , engineering , medicine
During biofabrication, a tissue scaffold may require temporary support. The aim of this study was to develop an approach of human thyroid cartilage scaffold temporal support formation. The scaffold 3D-model was based on DICOM images. XY plane projections were used to form scaffold supporting part. To verify the technique, collagen hydrogel was chosen as the main scaffold component. Gelatin was applied for the supporting part. To test the applicability of the approach, a model of thyroid cartilage scaffold with the support was printed. The scaffold corresponded to a given model, although some discrepancy in geometry was observed during verification by computed tomography.
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