INVESTIGATION OF RADIOSENSITIVITY OF GAMMA IRRADIATED ISONIAZID ANTIBIOTIC THROUGH EPR SPECTROSCOPY | Zendy

Kerem Sütçü | Zendy; Y. Emre Osmanoğlu | Zendy; Fırat Akbalık | Zendy

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INVESTIGATION OF RADIOSENSITIVITY OF GAMMA IRRADIATED ISONIAZID ANTIBIOTIC THROUGH EPR SPECTROSCOPY

Author(s) -

Kerem Sütçü,

Y. Emre Osmanoğlu,

Fırat Akbalık

Publication year - 2016

Publication title -

anadolu university journal of science and technology-a applied sciences and engineering

Language(s) - English

Resource type - Journals

ISSN - 1302-3160

DOI - 10.18038/aubtda.266472

Subject(s) - electron paramagnetic resonance , irradiation , spectroscopy , materials science , chemistry , radiation , radical , nuclear magnetic resonance , radiochemistry , analytical chemistry (journal) , physics , optics , nuclear physics , chromatography , organic chemistry , quantum mechanics

Dosimetric properties of gamma irradiated Isoniazid (IS) were investigated through Electron Paramagnetic Resonance (EPR) spectroscopy. While unirradiated IS presented no EPR signal, irradiated IS exhibited a significant EPR spectrum at room temperature. Some EPR parameters of obtained experimental spectrum were calculated. In order to describe the variation of EPR signal intensity with absorbed radiaiton dose, several mathematical equations were tried. It has been determined that the best fit of IS sample is with polinomial function (R 2 = 0.9675). Moreover time dependency of the intensity of the EPR signal of the irradiated sample was analysed to study the stability of the free radicals.

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