Anticoagulants and Antithrombotics

A substantial number of studies have provided evidence of the link between thrombosis and heart failure (HF). It is important to understand that thrombosis can be both a cause and a consequence of HF. HF itself promotes a state of hypercoagulability, and HF, its complications and progression may result from the consequences of a pre-existing prothrombotic state. Many HF patients routinely receive anticoagulant or antithrombotic therapy due to the presence of specific indications for their use, such as atrial fibrillation (AF) or coronary artery disease (CAD). However, the potential clinical benefit of using these agents in the management of HF itself remains a subject of active discussions.