Prostate Spinal Metastasis: An Update and Review.

Advanced prostate metastasis causes significant morbidity and mortality on the adult male population. This paper reviews the evidence regarding the efficacy of various treatment options currently present for patients with metastatic castration-resistant prostate cancer (mCRPC) to the spine. Treatment approaches for prostate spinal metastasis involves a multidisciplinary team. This paper is a review of all the viable treatment options available to patients who present with spinal mCRPC, including discussion on gaps in care and emerging treatments that may both address symptoms as well as facilitate local disease control. Despite multiple modalities of treatment, there is limited data to support a treatment paradigm that provides the most efficacious sequence of approved treatments for individual patients. Future studies that analyze these algorithms are needed to improve prostate metastatic care.