During Cardiopulmonary Bypass Release of Mediators and Their Effect on Pulmonary Function

Objective: The heart-lung machine, while playing an extremely important role in the development of cardiac surgery in particular restricts the use of negative effects on the lungs. The resulting postperfusion syndrome or inflammatory response of the body requires a long period of intensive care. In some cases, this may even lead to multiple organ failure or even death. This inflammatory response causes the investigation and to manifest coronary artery bypass grafting (CABG) is one of the most important points made in the case. Material and Methods: In the Cardiovascular Surgery Clinic, cardiopulmonary bypass (CPB) is applied to a control group of 25 patients CABG, coronary artery bypass surgery without CPB implementation of the 10 patients were enrolled into the study. Patients, plasma vascular endothelial growth factor (VEGF) and elastase levels were measured. Pulmonary function test with FEV1, FVC 1Celal Bayar Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Manisa, Türkiye 2Akdeniz Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, Antalya, Türkiye 3Akdeniz Üniversitesi, Biyokimya Anabilim Dalı, Antalya, Türkiye 4AkdenizÜniversitesi Tıp Fakültesi, Kalp Damar Cerrahisi Anabilim Dalı, Antalya, Türkiye Yazışma Adresi Correspondence Address Hakan KESKİN Akdeniz Üniversitesi Tıp Fakültesi, Göğüs Cerrahisi Anabilim Dalı, Antalya, Türkiye E-posta: opdrhakankeskin@hotmail.com.tr